Searchable abstracts of presentations at key conferences in endocrinology

ea0063p589 | Diabetes, Obesity and Metabolism 2 | ECE2019

Discrete choice and SF-36 estimates of patient quality of life and benefits of leptin replacement therapy (LRT) in generalized and partial lipodystrophy (GL, PL)

Ali Omer , Cook Keziah , Lee Don , Shampanier Kristina , Tuttle Edward , Bradt Pamela

We report new estimates of the disutility associated with GL and PL, and the quality of life (QoL) impact of leptin replacement therapy (LRT) based on two methods. The first approach estimates utility decrements associated with a range of impairments related to lipodystrophy through a discrete choice experiment (DCE) conducted with members of the general public; the second elicits QoL estimates from 8 PL patients using the SF-36 instrument. To characterize QoL consequences of ...